The Children's Hospital of Philadelphia;The Childrens Hospital of Philadelphia
发明人:
Camire, Rodney M.,Bunce, Matthew W.,Bos, Mettine H. A.
申请号:
AU2012323928
公开号:
AU2012323928A1
申请日:
2012.10.15
申请国别(地区):
AU
年份:
2014
代理人:
摘要:
In accordance with the instant invention, Factor V peptides for the modulation of thrombin generation are provided. In a particular embodiment, the peptide has at least 80% homology with SEQ ID NO: 1, 2, 3 or 4. Nucleic acid molecules encoding the peptides are also encompassed by the instant invention. Compositions comprising at least one peptide and/or nucleic acid of the instant invention and at least one pharmaceutically acceptable earner are also provided. The compositions may further comprise at least one other anti-thrombosis compound.