TOBLER, HANS,WALTER, HARALD,CORSI, CAMILLA,EHRENFREUND, JOSEF,GIORDANO, FANNY,ZELLER, MARTIN
申请号：
CA2631973
公开号：
CA2631973C
申请日:
2006.12.11
申请国别(地区):
CA
年份:
2015
代理人:
摘要：
The present invention relates to a novel a process for the preparation of thecompound of the general formula (I), wherein R1 and R2 are independently H orC1-6 alkyl, which comprises treating with a reducing agent either a compoundof the general formula (II), wherein R1 and R2 have the meanings given for thecompound of the formula (I), R3 is H or C1-4alkyl and Ph is phenyl, or acompound of the general formula (III), wherein R1, R2, R3 and Ph have themeanings given for the compound of the formula (II), the reducing agent beingeffective to cleave the benzyl moiety Ph-CH(R3)- from the benzylamino moietyPhCH(R3)NH- in the compound of the formula (II) or in the compound of theformula (III) to leave an amino group and, in addition, in the case of thecompound of the formula (III), to reduce both the 2,3-double bond and thedouble bond joining the R1R2C- moiety to the 9-position of the benzonorbornenering to single bonds. It also relates to processes for the preparation of thecompounds (II) and (III) and their precursors and to the compounds (II) and(III) themselves and certain of their precursors, which are novel compounds.The compounds (I) are useful for the preparation of various fungicidalheterocyclyl-carboxylic acid benzonorbornen-5-yl-amides.
