CONSIGLIO NAZIONALE DELLE RICERCHE;FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA
发明人:
Pietro Ferraro,Sara Coppola,Andrea Finizio,Simonetta Grilli,Veronica Vespini,Paolo Antonio Netti,Raffaele Vecchione,Eliana Esposito
申请号：
US14767073
公开号：
US09561355B2
申请日:
2014.02.11
申请国别(地区):
US
年份:
2017
代理人:
摘要：
There is described a method for making an array of micro-needles, comprising the steps of:depositing a plurality of drops of a liquid substance comprising a polymer on a surface of a starting substrate；positioning a pyroelectric substrate at a certain distance from the starting substrate in such a way that the drops deposited are positioned between said surface of the starting substrate and a surface of the pyroelectric substrate；varying the temperature of the pyroelectric substrate or a part thereof to induce on said surface of the pyroelectric substrate a charge density such that starting from the drops deposited, under the effect of an electrodynamic force, respective cones are formed having a tip facing towards the pyroelectric substrate；determining a consolidation of the cones, to form said micro-needles, preventing the tip of said cones from contacting said surfaces of the pyroelectric substrate.
