The present invention relates to an N-phenyl-N'-phenoxycarbonyl-phenylsulfonhydrazide derivative which has excellent activity in inhibiting PGE2 production, a method for preparing the same, and a pharmaceutical composition comprising the same as an active ingredient. The N-phenyl-N'-phenoxycarbonyl-phenylsulfonhydrazide derivative of the present invention can be effectively used for the treatment or prevention of inflammation, arthritis, high fever, pain, cancer, stroke or bone diseases.Cette invention concerne un dérivé deN-phényl-N'-phénoxycarbonyl-phénylsulfonhydrazide ayant une excellente activité d'inhibition de la production de PGE2, son procédé de préparation, et une composition pharmaceutique le contenant à titre de principe actif. Le dérivé de N-phényl-N'-phénoxycarbonyl-phénylsulfonhydrazide selon l'invention peut être utilisé efficacement pour traiter ou prévenir l'inflammation, l'arthrite, une forte fièvre, la douleur, le cancer, un accident vasculaire cérébral ou les maladies osseuses.본 발명은 PGE2 생성을 저해하는 활성이 우수한 N-페닐-N'-페녹시카르보닐-페닐설폰하이드라자이드 유도체, 그의 제조방법 및 그를 유효성분으로 포함하는 약제학적 조성물에 관한 것이다. 본 발명의 N-페닐-N'-페녹시카르보닐-페닐설폰하이드라자이드 유도체는 염증, 관절염, 고열, 통증, 암, 뇌졸중 또는 뼈 질환의 치료 또는 예방에 효과적으로 사용될 수 있다.
