Aziende Chimiche Riunite Angelini Francesco A.C.R.A.F. S.P.A.
发明人:
Alisi, Maria Alessandra,Cazzolla, Nicola,Garofalo, Barbara,Furlotti, Guido,Magaro', Gabriele,Ombrato, Rosella,Mancini, Francesca,Magaro, Gabriele
申请号:
AU2013224313
公开号:
AU2013224313A1
申请日:
2013.02.08
申请国别(地区):
AU
年份:
2014
代理人:
摘要:
1 H-indazole-3-carboxamide compounds as glycogen synthase kinase 3 beta inhibitors. The present invention relates to the 1 H-indazole-3-carboxamide compounds for use as glycogen synthase kinase 3 beta (GSK-33) inhibitors and to their use in the treatment of GSK-3p-related disorders such as, for example, (i) insulin-resistance disorders; (ii) neurodegenerative diseases; (iii) mood disorders; (iv) schizophrenic disorders; (v) cancerous disorders; (vi) inflammation, (vii) substance abuse disorders; and (viii) epilepsies.