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2-Oxo-oxazolidin-3,5-diyl antibiotic derivatives
专利权人:
Actelion Pharmaceuticals Ltd.
发明人:
HUBSCHWERLEN, Christian,RUEEDI, Georg,SURIVET, Jean-Philippe,ZUMBRUNN ACKLIN, Cornelia
申请号:
ES12791863
公开号:
ES2581056T3
申请日:
2012.11.07
申请国别(地区):
ES
年份:
2016
代理人:
摘要:
A compound of formula I ** Formula ** in which R1a represents H or carboxy and R1b represents H, or R1a and R1b together represent the group * -C (O) -NH-S- or the group * -C (OH )>; = NS-, in which "*" represents the junction point of R1a and " represents the junction point of R1b; R2 represents H, (C1-C3) alkyl, hydroxy (C1-C3) alkyl, benzyl or cycloalkyl (C3-C5); R3 represents H or halogen; U represents N or CR4; wherein R4 is H or (C1-C3) alkoxy; A represents CH, B represents NH, m represents 1 or 2 and n represents 1 or 2; or A represents N, B is absent, m represents 2 and n represents 2; Y represents CH or N; and Q represents O or S; or a salt of said compound.Un compuesto de fórmula I**Fórmula** en la que R1a representa H o carboxi y R1b representa H, o R1a y R1b representan junto el grupo *-C(O)-NH-S- o el grupo *-C(OH)>;=N-S- , en el que "*" representa el punto de unión de R1a y " " representa el punto de unión de R1b; R2 representa H, alquilo (C1-C3), hidroxi-alquilo (C1-C3), bencilo o cicloalquilo (C3-C5); R3 representa H o halógeno; U representa N o CR4; en el que R4 es H o alcoxi (C1-C3); A representa CH, B representa NH, m representa 1 o 2 y n representa 1 o 2; o A representa N, B está ausente, m representa 2 y n representa 2; Y representa CH o N; y Q representa O o S; o una sal de dicho compuesto.
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