HUNTLEY, C. FREDERICK M.,KATAISTO, ERIK WAYNE,REISCH, HELGE ALFRED,SHARMA, ARCHANA,STYMIEST, JAKE LARRY
申请号：
CA2977732
公开号：
CA2977732A1
申请日:
2016.03.09
申请国别(地区):
CA
年份:
2016
代理人:
摘要：
The present disclosure provides acetate salts of buprenorphine, and its anhydrates, solvates, hydrates, and crystalline forms thereof, where the acetate salts of buprenorphine are essentially free of impurities. The disclosure further provides method of preparing the acetate salts, buprenorphine free base prepared from the acetate salts, other salts prepared from the free base, and pharmaceutical compositions thereof essentially free of impurities.
