C. Frederick M. HUNTLEY,Erik Wayne KATAISTO,Helge Alfred REISCH,Archana SHARMA
申请号：
US16446397
公开号：
US20190314364A1
申请日:
2019.06.19
申请国别(地区):
US
年份:
2019
代理人:
摘要：
The present disclosure provides acetate salts of buprenorphine, and its anhydrates, solvates, hydrates, and crystalline forms thereof, where the acetate salts of buprenorphine are essentially free of impurities. The disclosure further provides method of preparing the acetate salts, buprenorphine free base prepared from the acetate salts, other salts prepared from the free base, and pharmaceutical compositions thereof essentially free of impurities.
