BOLLI, MARTIN,BOSS, CHRISTOPH,BROTSCHI, CHRISTINE,GUDE, MARKUS,HEIDMANN, BIBIA,SIFFERLEN, THIERRY,WILLIAMS, JODI T.
申请号：
PH12015500627
公开号：
PH12015500627A1
申请日:
2015.03.20
申请国别(地区):
PH
年份:
2015
代理人:
摘要：
The present invention relates to [ortho bi-(hetero-)aryl]-[2-(meta bi-(hetero-)aryl)-pyrrolidin-1-yl]- methanone derivatives of formula (I) wherein R, and the rings A1 A2 and A3 are as described in the description, to pharmaceutically acceptable salts thereof, to their preparation, to pharmaceutical compositions containing one or more compounds of formula (I), and to their use as pharmaceuticals, especially to their use as orexin receptor antagonists.
