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Method of inhibiting vascular intimal hyperplasia using stent
专利权人:
Ikuo Omura
发明人:
Ikuo Omura,Zhen Yu Jin,Shuzo Yamashita,Hiroo Iwata,Akira Mochizuki
申请号:
US13561828
公开号:
US08968392B2
申请日:
2012.07.30
申请国别(地区):
US
年份:
2015
代理人:
摘要:
A method of inhibiting vascular intimal hyperplasia including: placing a stent within a blood vessel, the stent having a stent body of a cylindrical configuration having outer and inner surfaces with a diamond-like thin film coated on the surfaces, a first coated layer coating at least the outer surface of the stent body, the first coated layer being prepared of a first composition comprising a biodegradable polymer and a vascular intimal hyperplasia inhibitor of a kind, comprising argatroban, which does not inhibit proliferation of endothelial cells, the weight composition ratio of the polymer to the vascular intimal hyperplasia inhibitor being within the range of 8:2 to 7:3, and a second coated layer and causing argatroban to be released from the stent to thereby inhibit the vascular intimal hyperplasia without inhibiting proliferation of endothelial cells.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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