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Drug sustained release stent
专利权人:
株式会社日本ステントテクノロジー;学校法人東海大学;岩田 博夫
发明人:
小村 育男,金 貞玉,山下 修蔵,岩田 博夫,望月 明
申请号:
JP2013021873
公开号:
JP5636451B2
申请日:
2013.02.07
申请国别(地区):
JP
年份:
2014
代理人:
摘要:
A stent includes a stent body of a cylindrical configuration having outer and inner surfaces, a first coated layer coating at least the outer surface, and a second coated layer coating substantially completely over the first coated layer. The first coated layer is prepared of a first composition comprising a polymer and a vascular intimal hyperplasia inhibitor (preferably argatroban) of a kind, which does not inhibit proliferation of endothelial cells, the weight compositional ratio of the polymer to the inhibitor being within the range of 8 : 2 to 3 : 7. On the other hand, the second coated layer is prepared of a polymer alone or a second composition comprising a polymer and a drug, the weight compositional ratio of the drug to 80 % by weight of the polymer being less than 20 % by weight.
来源网站:
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