Provided are an image processing system, an image processing method, and a program for adjusting an image quality of a fluorescent light motion image. An image obtaining section that obtains a high image-quality motion image and a low image-quality motion image in which a same subject is captured simultaneously a motion calculating section that calculates a motion of the subject in the high image-quality motion image, from the high image-quality motion image and an image adjusting section that generates a motion image resulting from adjusting an image quality of the low image-quality motion image, based on the motion calculated by the motion calculating section are included, to adjust an image quality of a low image-quality motion image. Accordingly, the image quality of a low image-quality image can be improved.