KYLE, DONALD J.,GOEHRING, R. RICHARD,FUNDYTUS, MARIAN E.
申请号:
CA2731939
公开号:
CA2731939C
申请日:
2009.07.30
申请国别(地区):
CA
年份:
2017
代理人:
摘要:
The present invention is directed to Buprenor-phineAnalog compounds of the Formula I, Formula II or FormulaIII shown below, wherein R1, R2, R8, R3, R3a, R3b, X, Zand Y are as defined herein., R1 H3CO (I) OCH3 OCH3 (III)Compounds of the Invention are useful for treating pain andother conditions modulated by activity of opioid and ORL1receptors.