KYLE, DONALD J.,GOEHRING, R. RICHARD,FUNDYTUS, MARIAN E.
申请号:
PL09789036
公开号:
PL2326651T3
申请日:
2009.07.30
申请国别(地区):
PL
年份:
2014
代理人:
摘要:
The present invention is directed to Buprenorphine Analog compounds of the Formula I, Formula II or Formula III shown below, wherein R 1 , R 2 , R 8 , R 3 , R 3a , R 3b , X, Z and Y are as defined herein. Compounds of the Invention are useful for treating pain and other conditions modulated by activity of opioid and ORL1 receptors.