Andrew Ratcliffe;Richard John Harrison;Sally Oxenford;Claudio Dagostin;Cyrille Boussard;Nigel Ramsden;Kathryn Bell;Nelly Piton
发明人:
Nigel Ramsden,Richard John Harrison,Sally Oxenford,Kathryn Bell,Nelly Piton,Claudio Dagostin,Cyrille Boussard,Andrew Ratcliffe
申请号：
US13503083
公开号：
US20120252779A1
申请日:
2010.10.19
申请国别(地区):
US
年份:
2012
代理人:
摘要：
The invention relates to compounds of formula (I)wherein X1 to X5, Y, Z1 to Z3, and R have the meaning as cited in the description and the claims. Said compounds are useful as JAK inhibitors for the treatment or prophylaxis of immunological, inflammatory, autoimmune, allergic disorders, and immunologically-mediated diseases. The invention also relates to pharmaceutical compositions including said compounds, the preparation of such compounds as well as the use as medicaments.
