RAMSDEN, NIGEL,HARRISON, RICHARD JOHN,OXENFORD, SALLY,BELL, KATHRYN,PITON, NELLY,DAGOSTIN, CLAUDIO,BOUSSARD, CYRILLE,RATCLIFFE, ANDREW
申请号：
SG2012029310
公开号：
SG180478A1
申请日:
2010.10.19
申请国别(地区):
SG
年份:
2012
代理人:
摘要：
The present invention relates to compounds of formula (I) wherein X1 to X5, Y, Z1 to Z3, and R have the meaning as cited in the description and the claims. Said compounds are useful as JAK inhibitors for the treatment or prophylaxis of immunological, inflammatory, autoimmune, allergic disorders, and immunologically-mediated diseases. The invention also relates to pharmaceutical compositions including said compounds, the preparation of such compounds as well as the use as medicaments.
