COMPOSITIONS AND METHODS FOR SPECIFIC REACTIVATION OF HIV LATENT RESERVOIR

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专利权人:

发明人:

Wenhui Hu,Kamel Khalili,Yonggang Zhang

申请号：

US15705825

公开号：

US20180073018A1

申请日:

2017.09.15

申请国别(地区):

US

年份:

2018

代理人:

摘要：

The present invention relates to compositions and methods for reactivation of HIV in vivo or in vitro. latently infected cell. In one embodiment, the present invention uses the CRISPR/Cas9 system in combination with the MS2 bacteriophage coat protein-mediated synergistic activation mediator (SAM) system to provide enhanced transcriptional activation of the HIV genome.

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中国工程科技知识中心

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http://www.ckcest.cn/home/