LIU, YOUNG-JUN,VOO, KUI SHIN,BOVER, LAURA,TSURUSHITA, NAOYA,TSO, J. YUN,KUMAR, SHANKAR
申请号：
PE0003322013
公开号：
PE14032013A1
申请日:
2011.08.23
申请国别(地区):
PE
年份:
2014
代理人:
摘要：
Referring to an isolated Antibody which binds Ox40, characterized by comprising: a) a variable region of heavy chain that contains the amino acid sequence of CDR1 SEC ID no: 1.13 CDR2 includes SEC ID no: 2.14 CDr3 includes SEC ID no: 3.15 and (b) the variable region of light chain CDR1 Includes SEC ID no: 7.19 CDR2 includes SEC ID not 8,20 CDr3 includes SEC ID not 9.21.This Antibody is useful for the treatment of Cancer and autoimmune diseases.REFERIDO A UN ANTICUERPO AISLADO EL CUAL ENLAZA OX40, CARACTERIZADO POR QUE COMPRENDE: A) UNA REGION VARIABLE DE CADENA PESADA CDR1 QUE CONTIENE LA SECUENCIA DE AMINOACIDOS SEC ID NO: 1,13 CDR2 COMPRENDE SEC ID NO: 2,14 CDR3 COMPRENDE SEC ID NO: 3,15 Y B) LA REGION VARIABLE DE CADENA LIGERA CDR1 COMPRENDE SEC ID NO: 7,19 CDR2 COMPRENDE SEC ID NO 8,20 CDR3 COMPRENDE SEC ID NO 9,21. DICHO ANTICUERPO ES UTIL PARA EL TRATAMIENTO DE CANCER Y ENFERMEDADES AUTOIMUNES.
