Warszawski Uniwersytet Medyczny;INSTYTUT FARMACEUTYCZNY
发明人:
申请号:
EP15460037.3
公开号:
EP3124016A1
申请日:
2015.07.31
申请国别(地区):
EP
年份:
2017
代理人:
摘要:
The present invention relates to the antipsoriatic emulsion composition, especially in the form of a cream, comprising an effective therapeutic dose of cefazolin, the ingredients of the oil phase and the ingredients of the water phase, characterized by that(i) the ingredients of the oil phase include:- liquid paraffin or white petrolatum,- polyoxyethylene stearyl ether (21), and- cetostearyl alcohol;(ii) the ingredients of the oil phase include a buffer solution to maintain the pH value of the initial composition from 5 to 9, preferably in the range 6 - 8,(iii) optionally, comprising an additional amphiphilic nonionic emulsifier, and other soluble/water miscible excipients,wherein water content accounts for 50 to 80% by weight of the composition.