Martin Gleave,Paul S. Rennie,Hideaki Miyake,Colleen Nelson
申请号：
US14027693
公开号：
US09074209B2
申请日:
2013.09.16
申请国别(地区):
US
年份:
2015
代理人:
摘要：
A method for treating an individual suffering from a cancer comprising administering to the individual i) a chemotherapeutic agent, and ii) one antisense oligonucleotide having nucleotides in the sequence set forth in Seq. ID No. 4 and which antisense oligonucleotide has a phosphorothioate modification that increases the stability thereof in vivo, wherein the cancer expresses testosterone-repressed prostate message-2 (TRPM-2), thereby treating said individual.
