MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH
发明人:
WANG, SHANGFENG,YASZEMSKI, MICHAEL J.,LU, LICHUN,CURRIER, BRADFORD L.
申请号:
CA2588351
公开号:
CA2588351C
申请日:
2005.11.18
申请国别(地区):
CA
年份:
2013
代理人:
摘要:
Poly(propylene fumarate) is copolymerized with poly(caprolactone) diol toproduce a block copolymer of poly(propylene fumarate) and poly(caprolactone).The biocompatible and bioresorbable block copolymer of poly(propylenefumarate) and poly(caprolactone) is useful in the fabrication of injectableand in~ situ hardening scaffolds for tissue and/or skeletal reconstruction.The block copolymer can be crosslinked by redox or photo-initiation, with orwithout an additional crosslinker. Thus, the copolymer is both self-crosslinkable (without the use of any crosslinkers) and photocrosslinkable (inthe presence of photons such as UV light).