Ivan Coulter,Bernard Francis McDonald,Vincenzo Aversa
申请号：
US14723314
公开号：
US20150342893A1
申请日:
2015.05.27
申请国别(地区):
US
年份:
2015
代理人:
摘要：
An oral celecoxib formulation, the formulation being a multiple minibead formulation wherein the minibeads comprise a hydrogel-forming polymer matrix in which are distributed celecoxib, a polyoxyethylated non-ionic surfactant and an anionic surfactant, the minibeads when combined with water being capable of releasing self-assembly structures comprising surfactant and celecoxib.The formulation may be used for treating colorectal cancer, e.g. for inhibiting, reducing or delaying the initiation and/or progression of colorectal cancer, or for use in reversing colorectal cancer, reducing the burden of colorectal cancer and/or inducing remission of colorectal cancer, or for inhibiting, reducing or delaying metastasis of a colorectal cancer.
