Provided is a treatment device for an endoscope. According to the present invention, the treatment device comprises: an insertion unit having an insertion pipe in which a wire having a connector formed on a front end is disposed therein to be able to reciprocally move, and inserted into a channel of an endoscope; a clip having front ends bent to face each other and a plurality of tongs crossing each other; a clip operation unit having one end caught in and connected to the clip and the other end connected to the connector, and configured to open or close the clip; a cartridge having a first accommodation unit on which the pair of tongs of the clip are opened, a second accommodation unit on which the clip operation unit is disposed, and a third accommodation unit on which a moving pipe separating unit having an end facing the first accommodation unit is disposed, and configured to accommodate the clip operation unit therein together with the clip; and a guide unit configured to guide a front end of the clip switched from an opened state to a closed state while passing through the first accommodation unit to be stopped by being in contact with an end of the moving pipe separating unit. The guide unit comprises: a pair of arrangement units recessed at a predetermined depth in an area corresponding to a space between the first accommodation unit and the second accommodation unit; a pair of elastic pieces extending in a predetermined length to be closed to the end of the moving pipe separating unit from a contact guide surface formed on the first accommodation unit and disposed on the pair of arrangement units; and a clip support step protruding from an inner surface of the pair of elastic pieces facing each other. According to the present invention, it is possible to fundamentally prevent the connector from being separated from a clip connection body when the clip is opened and closed.내시경용 처치구 장치를 제공한다. 본 발명은 선단에 접속구를 갖는 와이어가 왕복이동가능하게 내부배치된 삽입관을 갖추어 내시경의 채널로 삽입되는 삽입부