The present invention relates to a composition comprising ribose and caffeine as active ingredients, having a continuous fatigue prevention function, restoring the body's high-energy phosphate substance level, and helping to increase energy. The composition comprises 1 to 99.9 parts by weight of ribose and 0.1 to 99 parts by weight of coffee, or 1 to 99.99 parts by weight of ribose and 0.01 to 99 parts by weight of caffeine.本発明は、リボースとカフェインを有効成分とする、持続的な疲労防止機能を有すると共に、体の高エネルギーリン酸物質レベルを回復し、エネルギーの増加に役に立つ組成物に関する。前記組成物は、リボース1~99.9重量部とコーヒー0.1~99重量部、又は、リボース1~99.99重量部とカフェイン0.01~99重量部を含む。