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1-cyclohexyl-2-phenylaminobenzimidazoles as mIDH1 inhibitors for the treatment of tumors
专利权人:
Bayer Pharma Aktiengesellschaft
发明人:
Hartmut Rehwinkel,Sonja Anlauf,Duy Nguyen,Olaf Panknin,Marcus Bauser,Katja Zimmermann,Stefan Kaulfuss,Roland Neuhaus,Paul Matthew Blaney,Gianna Toschi
申请号:
US15520384
公开号:
US10137110B2
申请日:
2015.10.21
申请国别(地区):
US
年份:
2018
代理人:
摘要:
The present invention relates to benzimidazol-2-amines of general formula (I) in which R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, R11 and R12 are as defined herein, to methods of preparing said compounds, to intermediate compounds useful for preparing said compounds, to pharmaceutical compositions and combinations comprising said compounds and to the use of said compounds for manufacturing a pharmaceutical composition for the treatment or prophylaxis of a disease, in particular of neoplasms, as a sole agent or in combination with other active ingredients.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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