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Benzimidazol-2-amines as mIDH1 inhibitors
专利权人:
发明人:
Hartmut Rehwinkel,Olaf Panknin,Sven Ring,Sonja Anlauf,Holger Siebeneicher,Duy Nguyen,Wolfgang Schwede,Marcus Bauser,Katja Zimmermann,Stefan Kaulfuss,Roland Neuhaus,Paul Matthew Blaney
申请号:
US15118154
公开号:
US09957235B2
申请日:
2015.02.10
申请国别(地区):
US
年份:
2018
代理人:
摘要:
The present invention relates to benzimidazol-2-amines of general formula (I), in which R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, R11 and R12 are as defined herein, to methods of preparing said compounds, to intermediate compounds useful for preparing said compounds, to pharmaceutical compositions and combinations comprising said compounds and to the use of said compounds for manufacturing a pharmaceutical composition for the treatment or prophylaxis of a disease, in particular of neoplasms, as a sole agent or in combination with other active ingredients.
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