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PROCÉDÉ D'AJUSTEMENT DE DURETÉ DE MATÉRIAU DE BASE EN BÂTONNET COMPRENANT UN COMPOSÉ PEPTIDE LIPIDIQUE
专利权人:
Ltd.;Nissan Chemical Industries
发明人:
申请号:
EP16814231.3
公开号:
EP3311798A1
申请日:
2016.06.14
申请国别(地区):
EP
年份:
2018
代理人:
摘要:
There is provided a method for adjusting hardness of a stick-shaped base material comprising a lipid peptide compound. A method for adjusting hardness of a gelled solid base material for skin external application including a surfactant, water, and a lipid peptide compound including compounds of formulae (1) or the like,wherein R1 is a C9-23 aliphatic group, R2 is a hydrogen atom or the like, and R3 is a -(CH2)n-X group, n is a number from 1 to 4, and X is amino group, and the method characterized by comprising adding a pH adjuster to a solution in which the solid base material for skin external application is dissolved, or a solution including a surfactant, water, and a lipid peptide compound including at least one of compounds of formulae (1) to (3) or pharmaceutically usable salts of the compounds, to adjust the pH of the solution to a weak acidic to neutral range, and subsequently, causing gelation of the solution to form a solid base material for skin external application.
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