Luke R. Schenck,David J. Lamberto,Joseph L. Kukura, II,Francisco J. Guzman,Aaron Cote,Athanas Koynov
申请号：
US16061513
公开号：
US20200261365A1
申请日:
2016.12.13
申请国别(地区):
US
年份:
2020
代理人:
摘要：
A process for preparing and isolating pharmaceutical active ingredient particles having a particle size of between about 0.1 and 30 microns, wherein a slurry comprising the active ingredient and one or more pharmaceutically acceptable excipients is fed into a thin film evaporator under suitable conditions for less than 10 minutes sufficient to generate solid matrix particles comprising active ingredient and one or more excipients, wherein the particles have less than 5% residual solvent.
