A preservation solution for the preservation of cells, tissues and/or organs, said solution comprising: (i) water for injection； (ii) at least one saccharide； (iii) at least one component with pH buffer properties； (iv) optionally at least one component with calcium transport blocking properties or an anti-calcium activity； (v) salicylic acid, in free form or in salt form, or aspirin； and (vi) glutamic acid, in free form or in salt form, or glutamine； provided that acetamide is absent and/or if aspirin is present glutamine is absent and if glutamine is present aspirin is absent. A solution for liver, kidney, small bowel and pancreas preservation comprising water for injection, a disaccharide (sucrose), a least one pH buffer (disodium phosphate and monosodium phosphate), at least one calcium transport or channel blocker (diltiazem), salicylic acid, in free form or in salt form, or aspirin, glutamic acid, in free form or in salt form, or glutamine. The formulation further comprising solutes, components effective against oxygen free radicals and a colloidal osmotic. The further components include lactobionic acid, potassium hydroxide, sodium hydroxide, glutathione, allopurinol and PEG. Use of solution as a flush preservation solution or a cold storage preservation solution, in particular for use in transplantation.
