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SODIUM SALT OF THE URIC ACID TRANSPORTER INHIBITOR AND ITS CRYSTALLINE FORM
专利权人:
发明人:
申请号:
RU2017142996
公开号:
RU2017142996A3
申请日:
申请国别(地区):
RU
年份:
2019
代理人:
摘要:
The present invention relates to a sodium salt of a uric acid transporter inhibitor and the crystalline form thereof. In particular, the present invention relates to the sodium salt of a uric acid transporter (URAT1) inhibitor, and the I-type crystal and the preparation method thereof. The present invention relates to 1-((6-bromo-quinoline-4-yl)thio)cyclobutyl sodium formate (the compound of formula (I)), and the I-type crystal and the preparation method thereof. The I-type crystal of the compound of formula (I) obtained in the present invention has a good crystal form stability and chemical stability, and the crystallization solvent used has a low toxicity and low residue, and can be better used in clinical treatment.
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