WANG PEIYUAN,STEC WOJCIECH,CLARK JEREMY,CHUN BYOUNG-KWON,SHI JUNXING,DU JINFA
申请号:
IN1301/KOLNP/2011
公开号:
IN2011KN01301A
申请日:
2011.03.26
申请国别(地区):
IN
年份:
2016
代理人:
摘要:
The present invention provides (i) a process for preparing a 2-deoxy-2-fluoro-2-methyl-D-ribonolactone derivative, (ii) conversion of the lactone to nucleosides with potent anti-HCV activity, and their analogues, and (iii) a method to prepare the anti-HCV nucleosides containing the 2-deoxy-2-fluoro-2-C-methyl-�-D-ribofuranosyl nucleosides from a preformed, preferably naturally-occurring, nucleoside.