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NAUJI DVICIKLINIAI DIHIDROCHINOLIN-2-ONO DARINIAI
专利权人:
F. Hoffmann-La Roche AG
发明人:
AEBI, Johannes,AMREIN, Kurt,FANTASIA, Serena,HORNSPERGER, Benoit,KUHN, Bernd,LIU, Yongfu,MAERKI, Hans P.,MAYWEG, Alexander,Mohr, Peter,SCALONE, Michelangelo,TAN, Xuefei,ZHOU, Mingwei
申请号:
LT12766628
公开号:
LT2758388T
申请日:
2012.09.20
申请国别(地区):
LT
年份:
2018
代理人:
摘要:
The invention provides novel compounds having the general formula (I) wherein R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, R11, R12, A1, A2 A3 and n are as described herein, compositions including the compounds and methods of using the compounds. The compounds of the present invention are useful as inhibitors of aldosterone synthase. The compounds may be used, for example, in the treatment or prophylaxis of chronic kidney disease, congestive heart failure, hypertension, primary aldosteronism and Cushing syndrome.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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