A capsule medical apparatus (1 21 31 41 51 61 71 81 101 121 131), comprising: a needle driving unit (6 36 105) that punctures an internal region of interest in a subject with an injection needle (3 23 33 53 63 83 103) and pulls out the injection needle (3 23 33 53 63 83 103) from the internal region of interest a liquid injection unit (8 107) that injects a liquid into the internal region of interest through the injection needle (3 23 33 53 63 83 103) that punctures the internal region of interest and a leak prevention unit (4 24, 26 39, 46 54 63 74 84 108 128 138) that prevents the liquid injected into the internal region of interest from leaking from the internal region of interest.