Claus Aagaard,Ida Rosenkrands,Truc Thi Kim Thanh Hoang,Peter Lawaetz Andersen
申请号：
US15306239
公开号：
US20170043003A1
申请日:
2015.04.09
申请国别(地区):
US
年份:
2017
代理人:
摘要：
The present invention is directed to a fusion protein, antigen cocktails and immunological compositions such as vaccines against infections caused by virulent mycobacteria, e.g. by Mycobacterium tuberculosis, Mycobacterium africanum, Mycobacterium bovis, Mycobacterium microti, Mycobacterium canettii, Mycobacterium pinnipedii or Mycobacterium mungi. The fusion protein, antigen cocktails and immunological compositions are based on proteins secreted by the ESAT-6 secretion system 1 (ESX-1) and are among the most immunodominant M. tuberculosis (MTB) antigens.
