A supplemented antacid formulation comprising at least one primary component and at least one supplemental component. In one embodiment, a primary component is selected from the group consisting of calcium carbonate, magnesium carbonate, and potassium bicarbonate, and a supplemental component is selected from the group consisting of L-glutamine, deglycyrrhizinated licorice, D-limonene, papain, ginger extract, zinc L-carnosine complex, and a probiotic blend. In one further embodiment, a supplemented antacid formulation comprises a plurality of primary components in combination with a plurality of supplemental components, wherein the primary components are selected from the group consisting of calcium carbonate, magnesium carbonate, and potassium bicarbonate, and the supplemental components are selected from the group consisting of L-glutamine, deglycyrrhizinated licorice, D-limonene, papain, ginger extract, zinc L-carnosine complex, and a probiotic blend.
