COMPOSE 2-AMINO -6-FLUORO-N- [5-FLUORO-PYRIDIN -3-YL] PYRAZOLO [1,5-A] PYRIMIDINE-3-CARBOXAMIDE UTILE COMME INHIBITEUR DE LA KINASE ATR, SA PREPARATION, DIFFERENTES FORMES SOLIDESET DERIVES RADIOMARQUES DE CELUI-CI
CHARRIER, JEAN-DAMIEN,DAVIS, CHRISTOPHER JOHN,FRAYSSE, DAMIEN,ETXEBARRIA I JARDI, GORKA,PEGG, SIMON,PIERARD, FRANCOISE,PINDER, JOANNE,STUDLEY, JOHN,ZWICKER, CARL,SANGHVI, TAPAN,WALDO, MICHAEL,MEDEK, A
申请号：
CA2932757
公开号：
CA2932757A1
申请日:
2014.12.05
申请国别(地区):
CA
年份:
2015
代理人:
摘要：
The present invention relates to compounds useful as inhibitors of ATR protein kinase. The invention relates to pharmaceutically acceptable compositions comprising the compounds of this invention； methods of treating of various diseases, disorders, and conditions using the compounds of this invention； processes for preparing the compounds of this invention； intermediates for the preparation of the compounds of this invention； and solid forms of the compounds of this invention. The compounds of this invention have formula I-A or I-B: wherein the variables are as defined herein.
