Sofia Karlstrom,Peter Soderman,Laszlo Rakos,Liselotte Ohberg,Karin Kolmodin,Lars Sandberg
申请号:
US13916701
公开号:
US09000183B2
申请日:
2013.06.13
申请国别(地区):
US
年份:
2015
代理人:
摘要:
Cyclohexane-1,2′-indene-1′,2″-imidazole compounds, therapeutically acceptable salts thereof, processes for preparation thereof, therapeutic uses of such compounds for treating Aβ-related pathologies such as Down's syndrome, β-amyloid angiopathy, Alzheimer's disease, memory loss, attention deficit symptoms associated with Alzheimer's disease, neurodegeneration associated with diseases such as Alzheimer's disease or dementia including dementia of mixed vascular and degenerative origin, pre-senile dementia, senile dementia and dementia associated with Parkinson's disease, progressive supranuclear palsy or cortical basal degeneration, methods of therapy using such compounds, and pharmaceutical compositions containing such compounds.