A method of complex treatment of patients with plaque psoriasis comprising the use of an immunomodulatory effect of the drug, in addition, designate berlition drug and 1 tablet of 600 mg once a day for 12-14 days, and apply appliqué silt sulfide peloids in conjunction with baths with a high concentration of mineral water brine type wherein peloids are used 38-40 ° C temperature with an exposure of 15-20 min after 10-14 day course of treatments, andbalneotherapy conducted at a dilution of the brine to about 40 g / l with a temperature of 37-38 ° C for 15-20 min after 12-14 day course of treatments.The invention relates to medicine, namely to dermatology and can be used to treat patients with plaque psoriasis.Current scientific evidence indicates immunological nature of psoriatic disease with genetic and environmental components. Immunopathogenesis psoriasis triggered by activation of T lymphocytes by dendritic epidermal cells, with the participation of secreted cytokines and chemokines. As a result of a complex immune cascade of interactions of specific molecular structures remodeling occurs in epidermal hyperproliferation form, aberrant keratinocyte differentiation, angiogenesis accelerated the development of inflammatory skin infiltration by leukocytes, macrophages, T cells. Modern immune response modifiers and prior known conventional basic drugs have several limitations in application, and can cause undesirable side effects. As a result, exacerbation of psoriasis is not always possible to stop quickly and efficiently. Since psoriasis is a chronic relapsing disease, improved methods of long-term effective and safe therapy continues to be relevant. Numerous studies have demonstrated the role of medical factors resort as an alternative to drug therapy. Natural factors have a fast and pronounced therapeutic and rehabilitative effect that helps reduce receiving pharmacological agents and reduces the likelihood of side effects and complications.Chosen as the prototype
