Disclosed is an irradiation device for insertion into an orifice of the body to provide photodynamic therapy. The device includes of a housing moulded from a resilient material and adapted to be fully inserted and secured in the orifice. The housing encloses an LED lamp system and a power source for powering the LED lamp system. The device is independently operational while located in the orifice. The housing comprises a first housing part for holding the power source and a second housing part for holding the LED lamp system, the first and second housing parts being separable and preferably being formed separately from the LED lamp system. The first housing part consists of a chamber for holding the power source and an opening into the chamber is provided through a resilient opening part, wherein the chamber is closed when the first housing part is joined to the second housing part.
