PROBLEM TO BE SOLVED: To provide a method for suitably performing priming and fluid replacement for the blood purification device using a pump that has a liquid delivery flow rate and flow rate accuracy suited to priming.SOLUTION: A blood purification device 1 includes: a blood purifier 20 that is equipped with a blood purification membrane 30 a blood circuit 10 that sends blood in a blood collection portion 21 to a primary side of the blood purification membrane using a blood pump 40 to return it to a blood return portion 23 a dialysis fluid supply circuit 91 that supplies a dialysis fluid to a secondary side of the blood purification membrane a dialysis fluid discharge circuit 92 that discharges the dialysis fluid from the secondary side of the blood purification membrane and a fluid replacement/priming circuit 12. The fluid replacement/priming circuit is configured to perform: a fluid replacement step of supplying the dialysis fluid in the dialysis fluid supply circuit to the blood circuit by a fluid replacement pump 170 and a priming step of using the fluid replacement pump to make the dialysis fluid in the dialysis fluid supply circuit pass through the blood purification membrane and flow out to the primary side, and to discharge the dialysis fluid in the blood circuit including the primary side into the dialysis fluid discharge circuit without passing through the blood purification membrane.COPYRIGHT: (C)2016,JPO&INPIT【課題】プライミングに適した送液流量と流量精度を有するポンプを用いて血液浄化装置のプライミングや補液を好適に行う方法を提供する。【解決手段】血液浄化装置1は、血液浄化膜30を備えた血液浄化器20を有し、血液ポンプ40により採血部21の血液を血液浄化膜の一次側を通り返血部23に戻す血液回路10と、透析液を血液浄化膜の二次側に供給する透析液供給回路91と、透析液を血液浄化膜の二次側から排出する透析液排出回路92と、補液・プライミング回路12とを有している。補液・プライミング回路は、補液ポンプ170により透析液供給回路の透析液を血液回路に供給する補液工程と、補液ポンプにより、透析液供給回路の透析液を血液浄化膜を通過させて一次側に流出させ、当該一次側を含む血液回路の透析液を血液浄化膜を通過させずに透析液排出回路に排出するプライミング工程と、を行えるように構成されている。【選択図】図1
