The present invention relates to a plasma-generation device for applying plasma to a human body, the device comprising a reservoir containing a gas, a plasma zone in fluid connection with the reservoir, and means for generating a plasma by electrical discharge in the plasma zone, wherein the gas comprises from 92% to 99.5% Helium and from 0.5% to 8% Argon； or the gas comprises from 95% to 99.5% Helium and from 1% to 20% Neon； or the gas comprises from 99.95% to 99.99% Helium and from 0.01% to 0.05% Oxygen.
