1. This list relates to o-phenyl and o-benciloxipalamino derivatives, which carry out pharmacological activities on A2D units, especially voltage dependent calcium channel a2d-1 subunits, the preparation process of these compounds, including their components, and their use in treatment, especially in treatment. To treat pain. 1. Claim 1: a general formula compound (1),X is selected from the link, - [C (r7491； r749595)] 8346-[CH832222].8346C（o）[CH832222]Q-，-[CH832222]-8346C（o）n（R761181）[CH832222]Q-，-[CH832226]-8346N（R7611c（o）[CH832222]Q-Y-[CH832222]-8346N（R7611]Q-；R749191 is replaced or not replaced by hydrogen, halogen, c8332183, 8331832626, alquenilo c8332228331, and c832283316； r74955 is selected from hydrogen, halogen, c831832626, or not replaced； a. Alquenilo c83322831833226 is replaced or not replaced； and c833228318326 is replaced or not replaced； orR761111 is selected from the substituted or unsubstituted hydrogen, c83321c831832626 or alquenilo c8328331833226 substituted or unsubstituted asphalt c8328331833226； e. Replace or not replace y-c (o) - c83218331832626 tar；P is equal to 0, 1, 2, 3, 4 or 5； q is equal to 0, 1, 2, 3, 4 or 5； Y1 es-c (R1 8304；； r830404 ')；1. When r830404 and r830404 'independently select hydrogen, c8328333183326c832626 are not replaced or not replaced, c8322833126 is replaced or not replaced, and c8302833183226 is replaced or not replaced； or r1830404 and r1830404 can be formed together with attached carbon atoms； a. Replace or not replace a bicycle； Y2 es-c (R1 830404 '' "r830404 ')；"In R1 83040" and r83040 ", not replaced or not replaced with hydrogen, c832183326 or not, alquenilo c83228331, or c83228326, or c832283318326； or, alternatively, r1830404 '' and r1830404 '； Connected to the carbon atom is a ring 12 electrode which is replaced or not replaced； n is 0 or 1； R 1 is selected from - nr8309； - r8309y-nr8309c (o) r830999；R2 was selected from substituted or unsubstituted arilo and substituted or unsubstituted isopropene； R3 was s
