NATIONAL INSTITUTE OF BIOLOGICAL SCIENCES; BEIJING
发明人:
ZHANG, ZHIYUAN,WANG, XIAODONG,SU, YANING,RUAN, HANYING,REN, YAN
申请号：
CA2972294
公开号：
CA2972294C
申请日:
2015.12.23
申请国别(地区):
CA
年份:
2018
代理人:
摘要：
The invention provides amides that inhibit cellular necrosis and/or human receptor interacting protein 1 kinase (RIP1), including corresponding sulfonamides, and pharmaceutically acceptable salts, hydrides and stereoisomers thereof. The compounds are employed in pharmaceutical compositions, and methods of making and use, including treating a person in need thereof with an effective amount of the compound or composition, and detecting a resultant improvement in the person's health or condition.
