RAMOT AT TEL-AVIV UNIVERSITY LTD.;KIMRON VETERINARY INSTITUTE;THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK
发明人:
LIPKIN, W. Ian,BRIESE, Thomas,MISHRA, Nischay,BACHARACH, Eran,ELDAR, Avi
申请号：
SG11201704887S
公开号：
SG11201704887SA
申请日:
2015.12.15
申请国别(地区):
SG
年份:
2017
代理人:
摘要：
The invention is directed to isolated Tilapia Lake Virus or TiLV, and isolated nucleic acids sequences and polypeptides thereof. The invention also relates to probes and primers, and to antibodies against antigens from TiLV, and use of these reagents for detecting the presence or absence of TiLV in an animal. The invention also relates to iRNAs which target nucleic acid sequences of TiLV. The invention is also related to immunogenic compositions, including antibodies and vaccines, for inducing an immune response against TiLV in an animal. The invention is also related to gene constructs and cells comprising TiLV and isolated nucleic acids sequences and polypeptides thereof for use in developing prophylactic and therapeutic agents.
