Method for measuring ATR inhibition mediated increases in DNA damage

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专利权人:

发明人:

Susanna Falcon,Philip Reaper,John Pollard,Nicola Curtin,Fiona Middleton,Tao Chen

申请号：

US14045373

公开号：

US08999632B2

申请日:

2013.10.03

申请国别(地区):

US

年份:

2015

代理人:

摘要：

The present relates to methods for detecting DNA damage in subjects treated with an ATR inhibitor. More specifically, this invention relates to a method for measuring changes in levels of γH2AX and/or pChk1Ser345 in, e.g., surrogate tissue cells, following ex vivo stimulation with a DNA damaging agent.

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中国工程科技知识中心

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