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SYNTHESIS OF COMPOUNDS USEFUL AS MODULATORS OF AMYLOID-BETA PRODUCTION
专利权人:
SATORI PHARMACEUTICALS; INC.
发明人:
FINDEIS, MARK
申请号:
NZ57708107
公开号:
NZ577081A
申请日:
2007.11.20
申请国别(地区):
NZ
年份:
2012
代理人:
摘要:
Disclosed is a method for preparing a compound of formula I, or a pharmaceutically acceptable salt thereof, comprising the steps of: (a) providing a compound of formula II (such as those obtained from plant extracts of black cohosh), and (b) converting the compound of formula II to the compound of formula I by an intramolecular dehydration reaction in the presence of a suitable acid (such as a carboxylic acid, a sulfonic acid, or a phosphoric acid) and wherein the substituents are as defined herein.
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