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immunogenic Compositions
专利权人:
ГЛЭКСОСМИТКЛАЙН БАЙОЛОДЖИКАЛЗ СА (BE)
发明人:
КОНТОРНИ Марио (IT),ГРАНДИ Гвидо (IT),МАЙОНЕ Доменико (IT),МАРГАРИТ И РОС Иммакулада (IT)
申请号:
RU2015106745
公开号:
RU2015106745A
申请日:
2013.10.03
申请国别(地区):
RU
年份:
2016
代理人:
摘要:
1. An immunogenic composition comprising one or more GBS conjugates and one or more antigens selected from: a) cell or cell-free pertussis antigen, b) tetanus toxoid, c) diphtheria toxoid, and d) inactivated poliovirus antigen, where each GBS conjugate is group B streptococcal capsular saccharide conjugated to a carrier protein. 2. The immunogenic composition of claim 1, wherein the GBS conjugates comprise: i) a conjugate comprising a capsular saccharide from GBS serotype Ia conjugated to a carrier protein; ii) a conjugate comprising a capsular saccharide from GBS serotype Ib conjugated to a carrier protein; and / or iii) a conjugate comprising a capsular saccharide from GBS serotype III conjugated to a carrier protein. 3. The immunogenic composition according to claim 2, comprising: i) a conjugate comprising a capsular saccharide from GBS serotype Ia conjugated to a carrier protein, ii) a conjugate representing a capsular saccharide from GBS serotype Ib conjugated to a carrier protein, iii) conjugate which is a capsular saccharide from GBS serotype III conjugated to a carrier protein and iv) diphtheria toxoid. 4. The immunogenic composition according to claim 2, comprising: i) a conjugate comprising a capsular saccharide from GBS serotype Ia conjugated to a carrier protein, ii) a conjugate representing a capsular saccharide from GBS serotype Ib conjugated to a carrier protein, iii) conjugate a capsular saccharide from GBS serotype III conjugated to a carrier protein; and iv) tetanus toxoid. 5. The immunogenic composition according to claim 2, comprising: i) a conjugate comprising a capsular saccharide from GBS serotype Ia conjugated to a carrier protein, ii) a conjugate representing1. Иммуногенная композиция, содержащая один или более конъюгатов GBS и один или более антигенов, выбранных из: а) клеточного или бесклеточного антигена коклюша, b) токсоида столбняка, с) токсоида дифтерии и d) антигена инактивированного полиовируса, где каждый конъюгат GBS представляет с
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