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나프티리딘 유도체 및 살진균제로서의 이의 용도
专利权人:
发明人:
크로울리 패트릭 젤프,도블러 마르쿠스,뮬러 우르스,윌리엄스 존
申请号:
KR1020057011925
公开号:
KR1011064730000B1
申请日:
2003.12.03
申请国别(地区):
KR
年份:
2012
代理人:
摘要:
general formula (I) of the invention is a fungicidal composition of the will.formula 1In Formula 1 above,W, X, Y and Z is one of N, others CR 8 and,R 8 is H, halo, C 1-4 alkyl, C 1-4 alkoxy or halo (C 1-4 ) and alkyl, with the proviso that X is CH, and Z is N, R, and this NHNH 2 , and R 1 is phenyl, R 2 is If Cl, W and Y are not both represented CCH 3 ,One of R and R 2 is NR 3 R 4 and the other is halo, C 1-8 alkyl, C 1-8 alkoxy, C 1-8 alkylthio, C 2-8 alkenyl, C 2-8 alkynyl or cyano,R 1 is aryl, morpholino, piperidino or pyrrolidino,R 3 and R 4 are independently selected from H, C 1-8 alkyl, C 2-8 alkenyl, C 2-8 alkynyl, aryl , aryl (C 1-8 ) alkyl, C 3-8 cycloalkyl, C 3-8 cycloalkyl (C 1 -6 ) alkyl, heteroaryl, heteroaryl (C 1-8 ) alkyl, NR 5 R 6 , and the stage R 3 and R 4 are both H or NR 5 R 6 does not represent, R 3 and R 4 together with one or more C 1-4 alkyl or C 1-4 alkoxy group optionally substituted with C 3-7 alkylene or C 3-7 to form a chain or alkenylene, R 3 and R 4 They are together with the nitrogen atom to which they know morpholine, thiomorpholine, thiomorpholine S- oxide ring, a thiomorpholine ring S- dioxide, piperazine or piperazine N- (C 1-4 ) alkyl (especially to form a N- methyl) ring, and,R 5 and R 6 are independently selected from H, C 1- 8 alkyl, C 2-8 alkenyl, C 2-8 alkynyl, aryl, aryl (C 1-8 ) alkyl, C 3-8 cycloalkyl, C 3-8 cycloalkyl (C 1-6 ) alkyl, heteroaryl or heteroaryl and (C 1-8 ) alkyl,all of the above alkyl, alkenyl, alkynyl or cycloalkyl groups or moieties (R 8 a excluded) is halogen, cyano, C 1-6 alkoxy, C 1-6 alkylcarbonyl, C 1-6 alkoxycarbonyl , C 1-6 haloalkoxy, C 1-6 alkylthio, tri (C 1-4 ) alkylsilyl, C 1-6 alkylamino, or C 1-6 may be optionally substituted with dialkylamino,All the above morpholine, thiomorpholine, piperidine Dean, piperazine and pyrrolidine rings C 1-4 , and optionally may be substitut
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