BAZIN-LEE Helene,BAZIN-LEE Helene,COE Diane Mary,COE Diane Mary,LAZARIDES Linos,LAZARIDES Linos,MITCHELL Charlotte Jane,MITCHELL Charlotte Jane,SMITH Stephen Allan,SMITH Stephen Allan,TRIVEDI Naimisha
申请号:
SI200931724
公开号:
SI2320905T1
申请日:
2009.08.07
申请国别(地区):
SI
年份:
2017
代理人:
摘要:
The present invention relates to compounds of formula (I): wherein R1 is C1-6alkylamino, or C1-6alkoxy R2 is a group having the structure: n is an integer having a value of 1 to 6 Het is a 6-membered saturated heterocycle containing one nitrogen atom wherein Het is attached to the -(CH2)n- moiety at any carbon atom of the heterocycle R3 is hydrogen, C1-8alkyl, or C3-7cycloalkylC0-6alkyl and salts thereof are inducers of human interferon. Compounds which induce human interferon may be useful in the treatment of various disorders, for example the treatment of allergic diseases and other inflammatory conditions for example allergic rhinitis and asthma, the treatment of infectious diseases and cancer, and may also be useful as vaccine adjuvants.