KLAVENESS, JO,NILSEN, NILS OLAV,BRAENDEN, JON ERIK,GODAL, ASLAK
申请号:
CA2416307
公开号:
CA2416307C
申请日:
2001.07.25
申请国别(地区):
CA
年份:
2013
代理人:
摘要:
The invention provides compounds for use in photochemotherapy or diagnosis,saidcompounds being branched alkyl esters or substituted alkyl esters of 5-aminolevulinic acid,or derivatives or pharmaceutically acceptable salts thereof. In particular,the inventionprovides compounds of formula (I): R2 2N-CH2COCH2-CH2CO-OR1 (wherein R1represents ana C1 or C2 alkyl group substituted by one or more aryl groups or monocyclic 5-7 memberedheteroaromatic groups, wherein the aryl and the heteroaromatic groups areoptionallysubstituted; and R2 represents a hydrogen atom; and pharmaceuticallyacceptable salts thereoffor use in diagnosis and photochemotherapy of disorders of abnormalities ofexternal orinternal surfaces of the body, and products and kits for performing theinvention.