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ESTERS DE L'ACIDE 5-AMINOLEVULINIQUE UTILISES COMME AGENTS PHOTOSENSIBILISATEURS EN PHOTOCHIMIOTHERAPIE
专利权人:
PHOTOCURE ASA
发明人:
KLAVENESS, JO,NILSEN, NILS OLAV,BRAENDEN, JON ERIK,GODAL, ASLAK
申请号:
CA2416307
公开号:
CA2416307C
申请日:
2001.07.25
申请国别(地区):
CA
年份:
2013
代理人:
摘要:
The invention provides compounds for use in photochemotherapy or diagnosis,saidcompounds being branched alkyl esters or substituted alkyl esters of 5-aminolevulinic acid,or derivatives or pharmaceutically acceptable salts thereof. In particular,the inventionprovides compounds of formula (I): R2 2N-CH2COCH2-CH2CO-OR1 (wherein R1represents ana C1 or C2 alkyl group substituted by one or more aryl groups or monocyclic 5-7 memberedheteroaromatic groups, wherein the aryl and the heteroaromatic groups areoptionallysubstituted; and R2 represents a hydrogen atom; and pharmaceuticallyacceptable salts thereoffor use in diagnosis and photochemotherapy of disorders of abnormalities ofexternal orinternal surfaces of the body, and products and kits for performing theinvention.
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中国工程科技知识中心
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http://www.ckcest.cn/home/

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